What Type Of Disorder Is Williams Syndrome?

Is Williams Syndrome Rare?

Williams syndrome is a rare disorder that affects males and females in equal numbers and infants of any race may be affected.

The prevalence of this disorder is approximately one in 10,000-20,000 births in the United States..

Is Williams syndrome a form of autism?

Autism spectrum disorders (ASD) and Williams syndrome (WS) both are neurodevelopmental disorders, each with a unique social phenotypic pattern.

Who has Williams syndrome?

Williams. Williams syndrome affects between 1 in 7,500 to 1 in 20,000 people at birth. Life expectancy is less than that of the general population, mostly due to the increased rates of heart disease.

What is an elfin face?

Elfin facies is a form of facies where the patient presents with facial characteristics bearing some similarities to those traditionally associated with elves. It is characterized by prominent forehead, widely spaced eyes, upturned nose, underdeveloped mandible, dental hypoplasia, and patulous lips.

Can a child be slightly autistic?

It’s a developmental disability that affects the way people communicate, behave, or interact with others. There’s no single cause for it, and symptoms can be very mild or very severe. Some children who are on the spectrum start showing signs as young as a few months old.

What is the life expectancy of someone with Williams syndrome?

Some people with Williams syndrome may have a reduced life expectancy due to complications of the disease (such as cardiovascular involvement). No studies specifically exist on life expectancy, although individuals have been reported to live into their 60s.

Is Williams syndrome similar to Down syndrome?

Williams syndrome has a very uneven cognitive profile with marked strengths and weaknesses. Similarly, peaks and troughs of ability are present in Down syndrome, although the profile is less extreme. Down syndrome is more common than Williams syndrome, occurring in 1 in 600-800 births.

How does Williams syndrome affect speech?

Communication difficulties: Most children with Williams syndrome develop speech skills later than other children their age. With intervention, most children develop the ability to communicate wants and needs effectively. In fact, for many children with Williams syndrome, expressive language may be a relative strength.

What is Pallister Killian syndrome?

Pallister-Killian mosaic syndrome is a multi-system disorder that is characterized by extremely weak muscle tone ( hypotonia ) in infancy and early childhood, intellectual disability , distinctive facial features, sparse hair, areas of unusual skin coloring (pigmentation), and other birth defects .

What are 3 types of Down syndrome?

There are three types of Down syndrome: trisomy 21 (nondisjunction), translocation and mosaicism.Trisomy 21, the most common type of Down syndrome, occurs when there are three, rather than two, number 21 chromosomes present in every cell of the body. … Translocation accounts for 4% of all cases of Down syndrome.More items…

Does Williams syndrome make you happy?

Abstract. Williams syndrome is a genetic disorder resulting in a variety of medical and developmental features, one of which is a frequent outward presentation of substantial happiness.

Is Williams Syndrome a neurological disorder?

Williams Syndrome (WS) is a rare genetic disorder characterized by mild to moderate delays in cognitive development or learning difficulties, a distinctive facial appearance, and a unique personality that combines over-friendliness and high levels of empathy with anxiety.

Why are people with Williams syndrome so happy?

Scientists realized it was related to the levels of oxytocin. They knew that oxytocin is involved in social/intimacy behaviors, like mother-child bonding or romantic encounters. And they found that people with Williams syndrome have a lot more oxytocin than everybody else, and that it fluctuates wildly in the brain.

Why is Williams syndrome called Williams syndrome?

Williams syndrome is caused by the deletion of genetic material from a specific region of chromosome 7. The deleted region includes 26 to 28 genes, and researchers believe that a loss of several of these genes probably contributes to the characteristic features of this disorder.

Can people with Williams syndrome get married?

Pober says few people with William’s syndrome marry, and even fewer have children. But this may be changing, Pober says. Now there are new social training programs for people with Williams.

Is ADHD the opposite of autism?

The two disorders also share at least some genetic risk factors. A new study published 13 August in Human Brain Mapping suggests that in the brain, however, autism and ADHD may result from distinct, even opposite, patterns of activity.

What happens if you are missing chromosome 16?

A chromosome 16 deletion is a rare genetic condition in which part of the genetic material is missing that makes up chromosome 16, one of the body’s 46 chromosomes. Like most other chromosome disorders, this increases the risk of birth defects, developmental delay and learning difficulties.

What are the signs and symptoms of Williams syndrome?

What are the symptoms of Williams syndrome?specific facial features like a wide mouth, small upturned nose, widely spaced teeth, and full lips.colic or feeding problems.attention deficit hyperactivity disorder (ADHD)learning disorders.inward bend of pinky finger.specific phobias.short stature.speech delays.More items…

At what age is Williams Syndrome diagnosed?

Williams syndrome is usually diagnosed before a child is 4 years old. Your doctor will do an exam and ask about your family medical history. Then the doctor will look for facial features like an upturned nose, wide forehead, and small teeth. An electrocardiogram (EKG) or ultrasound can check for heart problems.

What does someone with Williams Syndrome look like?

These features include a small upturned nose, long philtrum (upper lip length), wide mouth, full lips, small chin, and puffiness around the eyes. Blue and green-eyed children with Williams syndrome can have a prominent “starburst” or white lacy pattern on their iris. Facial features become more apparent with age.

What genes are missing in Williams syndrome?

What causes Williams syndrome? Williams syndrome is caused by a missing piece ( deletion ) of genetic material from a specific region of chromosome 7. The deleted region includes more than 25 genes . CLIP2, ELN, GTF2I, GTF2IRD1, and LIMK1 are among the genes that are typically deleted in people with Williams syndrome.